Primary Identifier | MGI:3056542 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Foxp1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 12, 13, and 14, that encode the forkhead DNA-binding domain, were replaced with a Neo cassette via homologous recombination. RT-PCR and immunohistochemistry confirmed absence of mRNA in embryos and protein in heart tissue. |