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Publication : Genetic mapping of Pim-1 putative oncogene to mouse chromosome 17.

First Author  Hilkens J Year  1986
Journal  Somat Cell Mol Genet Volume  12
Issue  1 Pages  81-8
PubMed ID  3003932 Mgi Jnum  J:8183
Mgi Id  MGI:56652 Doi  10.1007/BF01560730
Citation  Hilkens J, et al. (1986) Genetic mapping of Pim-1 putative oncogene to mouse chromosome 17. Somat Cell Mol Genet 12(1):81-8
abstractText  Pim-1 is a putative oncogene activated in T-cell lymphomas induced by Moloney and AKR mink cell focus forming (MCF) viruses. We have determined the chromosomal localization of the Pim-1 gene in mice by Southern blot analysis of DNAs obtained from a panel of mouse-Chinese hamster somatic cell hybrids. The Pim-1 gene was localized on chromosome 17, a chromosome frequently aberrant in T-cell lymphomas. Two chromosomal regions, containing sequences homologous to regions within the Pim-1 locus, were localized on chromosome 6 and 16.
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