First Author | Hilkens J | Year | 1986 |
Journal | Somat Cell Mol Genet | Volume | 12 |
Issue | 1 | Pages | 81-8 |
PubMed ID | 3003932 | Mgi Jnum | J:8183 |
Mgi Id | MGI:56652 | Doi | 10.1007/BF01560730 |
Citation | Hilkens J, et al. (1986) Genetic mapping of Pim-1 putative oncogene to mouse chromosome 17. Somat Cell Mol Genet 12(1):81-8 |
abstractText | Pim-1 is a putative oncogene activated in T-cell lymphomas induced by Moloney and AKR mink cell focus forming (MCF) viruses. We have determined the chromosomal localization of the Pim-1 gene in mice by Southern blot analysis of DNAs obtained from a panel of mouse-Chinese hamster somatic cell hybrids. The Pim-1 gene was localized on chromosome 17, a chromosome frequently aberrant in T-cell lymphomas. Two chromosomal regions, containing sequences homologous to regions within the Pim-1 locus, were localized on chromosome 6 and 16. |