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Protein Coding Gene : Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor

Primary Identifier  MGI:1353431 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  30052
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within peptide hormone processing; response to cold; and response to dietary excess. Located in extracellular space; secretory granule; and trans-Golgi network. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor).
PHENOTYPE: Mice homozygous for a null allele have behavioral/neurological defects as well as decreased body weight. [provided by MGI curators]
  • synonyms:
  • basic protein IA-4,
  • MGI:1306777,
  • MGC:19107,
  • AI848336,
  • Pcsk1n,
  • pancreas protein 3,
  • MGI:2147922,
  • proprotein convertase subtilisin/kexin type 1 inhibitor,
  • Pan3,
  • proSAAS,
  • expressed sequence AI848336

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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