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Allele : Tpbg<tm1(KOMP)Mbp> trophoblast glycoprotein; targeted mutation 1, Mouse Biology Program, UC Davis

Primary Identifier  MGI:5287729 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Tpbg
Transmission  Cell Line Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 1725 starting at position 85725652 and ending at position 85727377 of Chromosome 9 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele