| Primary Identifier | MGI:2670997 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 329065 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables palmitoyl-CoA 9-desaturase activity and stearoyl-CoA 9-desaturase activity. Involved in cellular response to nutrient and monounsaturated fatty acid biosynthetic process. Acts upstream of or within fatty acid biosynthetic process. Located in membrane. Orthologous to human SCD (stearoyl-CoA desaturase). PHENOTYPE: After myocardial infarction, mice homozygous for a knock-out allele show abnormal physiological neovascularization with decreased VEGF-A protein levels in the plasma and myocardium, lower plasma levels of proangiogenic cytokines, decreased NAD(P)H oxidase activity, and failure of AMPK activation in the infarcted heart. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
