| Primary Identifier | MGI:1925810 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 78560 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Involved in several processes, including positive regulation of canonical Wnt signaling pathway; regulation of establishment of blood-brain barrier; and sprouting angiogenesis. Acts upstream of or within angiogenesis; negative regulation of vascular endothelial growth factor signaling pathway; and positive regulation of endothelial cell migration. Located in cell surface and plasma membrane. Is expressed in several structures, including cardiovascular system; cerebral cortex; embryo mesenchyme; limb bud; and nose. Orthologous to human ADGRA2 (adhesion G protein-coupled receptor A2). PHENOTYPE: Mice homozygous for null mutations display fetal or perinatal lethality with CNS hemorrhage and angiogenic arrest in the CNS. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
