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Allele : Pml<tm1.1Ews> promyelocytic leukemia; targeted mutation 1.1, Eva W Stratford
Primary Identifier  MGI:6195046 Allele Type  Targeted
Attribute String  Not Specified Gene  Pml
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Two zinc-binding cysteine residues were substituted for two alanine residues located in the RING domain at positions 62 and 65 (C62A and C65A). A floxed neomycin resistance cassette was removed via cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Pml<C62A/C65A>,
  • Pml<C62A/C65A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories





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