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Allele : Ptk2<tm1Heen> PTK2 protein tyrosine kinase 2; targeted mutation 1, Herve Enslen

Primary Identifier  MGI:4437305 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ptk2
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector replaced alternative exons 13 and 14 with an frt flanked hygro cassette and floxed the alternative exon 16. A spontaneous deletion of 307 bp removed exon 15. This deletion is expected to produce a protein lacking the autophosphorylation site tyrosine 397. Production of a truncated protein was confirmed by western blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • FAK<delta>,
  • FAK<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele