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Publication : DLX2 (TES1), a homeobox gene of the Distal-less family, assigned to conserved regions on human and mouse chromosomes 2.

First Author  Ozçelik T Year  1992
Journal  Genomics Volume  13
Issue  4 Pages  1157-61
PubMed ID  1354641 Mgi Jnum  J:1725
Mgi Id  MGI:50251 Doi  10.1016/0888-7543(92)90031-m
Citation  Ozcelik T, et al. (1992) DLX2 (TES1), a homeobox gene of the Distal-less family, assigned to conserved regions on human and mouse chromosomes 2. Genomics 13(4):1157-61
abstractText  Dlx-2 (also called Tes-1), a mammalian member of the Distal-less family of homeobox genes, is expressed during murine fetal development in spatially restricted domains of the forebrain. Searching for a candidate neurological mutation that might involve this gene, we have assigned the human and mouse loci to regions of conserved synteny on human chromosome 2, region cen--q33, and mouse chromosome 2 by Southern analysis of somatic cell hybrid lines. An EcoRI dimorphism, discovered in common inbred laboratory strains, was used for recombinant inbred strain mapping. The results place Dlx-2/Tes-1 near the Hox-4 cluster on mouse chromosome 2.
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