First Author | Ozçelik T | Year | 1992 |
Journal | Genomics | Volume | 13 |
Issue | 4 | Pages | 1157-61 |
PubMed ID | 1354641 | Mgi Jnum | J:1725 |
Mgi Id | MGI:50251 | Doi | 10.1016/0888-7543(92)90031-m |
Citation | Ozcelik T, et al. (1992) DLX2 (TES1), a homeobox gene of the Distal-less family, assigned to conserved regions on human and mouse chromosomes 2. Genomics 13(4):1157-61 |
abstractText | Dlx-2 (also called Tes-1), a mammalian member of the Distal-less family of homeobox genes, is expressed during murine fetal development in spatially restricted domains of the forebrain. Searching for a candidate neurological mutation that might involve this gene, we have assigned the human and mouse loci to regions of conserved synteny on human chromosome 2, region cen--q33, and mouse chromosome 2 by Southern analysis of somatic cell hybrid lines. An EcoRI dimorphism, discovered in common inbred laboratory strains, was used for recombinant inbred strain mapping. The results place Dlx-2/Tes-1 near the Hox-4 cluster on mouse chromosome 2. |