| Primary Identifier | MGI:7616479 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Cdkl5 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 4. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exon 4 floxed. The KO allele created from this allele intends to replicate various human mutations associated with CDKL5 deficiency disorder (CDD) and early infantile epileptic encephalopathy 2 (EIEE2). |
