| Primary Identifier | MGI:107426 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 16157 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables interleukin-11 binding activity and interleukin-11 receptor activity. Acts upstream of or within several processes, including cytokine-mediated signaling pathway; decidualization; and natural killer cell differentiation. Predicted to be located in extracellular region and membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; immune system; and nervous system. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha). PHENOTYPE: Female homozygotes for targeted null mutations are infertile due to defective decidua formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
