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Publication : Mouse brain organization revealed through direct genome-scale TF expression analysis.

First Author  Gray PA Year  2004
Journal  Science Volume  306
Issue  5705 Pages  2255-7
PubMed ID  15618518 Mgi Jnum  J:91257
Mgi Id  MGI:3046355 Doi  10.1126/science.1104935
Citation  Gray PA, et al. (2004) Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science 306(5705):2255-2257
abstractText  In the developing brain, transcription factors (TFs) direct the formation of a diverse array of neurons and glia. We identifed 1445 putative TFs in the mouse genome. We used in situ hybridization to map the expression of over 1000 of these TFs and TF-coregulator genes in the brains of developing mice. We found that 349 of these genes showed restricted expression patterns that were adequate to describe the anatomical organization of the brain. We provide a comprehensive inventory of murine TFs and their expression patterns in a searchable brain atlas database.
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