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Publication : Early expression in mice of genetic resistance to intestinal amebiasis.

First Author  Anaya-Velázquez F Year  1990
Journal  Arch Invest Med (Mex) Volume  21 Suppl 1
Pages  53-6 PubMed ID  2136503
Mgi Jnum  J:3228 Mgi Id  MGI:51743
Citation  Anaya-Velazquez F, et al. (1990) Early expression in mice of genetic resistance to intestinal amebiasis. Arch Invest Med (Mex) 21 Suppl 1:53-6
abstractText  Some strains of mice are known to be relatively resistant to hepatic or intestinal amebic infections. In order to know if the intestinal resistance is expressed few hours after infection, we inoculated axenic amebae in three inbred strains of mice either by direct intracecal injection or by infection of a washed-closed cecal loop. We found that amebae do not survive in conventional animals but they colonize longer in animals with the cecal loop. However, the survival was low after 24 hours postinfection. Balb/c mice were more susceptible and CBA mice more resistant. Our results suggest that genetic resistance to intestinal amebiasis is expressed in mice in the early phases of infection.
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