Primary Identifier | MGI:1330349 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 20760 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within response to estradiol. Located in cytoplasm and nucleus. Is expressed in ureteric trunk. PHENOTYPE: Homozygous knockout affects sensitivity to oxidative stress, resulting in increased kidney damage and fibrosis after ischemia-reperfusion injury and unilateral ureteral obstruction, respectively. [provided by MGI curators] |