Primary Identifier | MGI:7263355 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TcrbM38)330Biat |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene expresses a Tcrb clone specific for the M38-derived epitope of MCMV. The "Mini" mouse is transgenic for the rearranged hybridoma Tcrb chain only, which was expressed by nearly 100% of the CD8 T cells, while the Tcra chain is of endogenous origin. This increases the percentage of naïve M38-specific CD8 T cells from undetectable levels in C57BL/6 mice to âŒ10% of the total. |