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Allele : Slc41a2<em1(IMPC)J> solute carrier family 41, member 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6187996 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc41a2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGGATCTGTGAAGGTCGACT and CATTACATACAAGATCATTA, which resulted in a 467 bp deletion beginning at Chromosome 10 position 83,300,925 bp and ending after 83,301,391 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000295326 (exon 5) and 322 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 245 and early truncation 1 amino acid later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele