|  Help  |  About  |  Contact Us

Allele : Cflar<tm1.2Pope> CASP8 and FADD-like apoptosis regulator; targeted mutation 1.2, Richard M Pope

Primary Identifier  MGI:4868693 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cflar
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted just upstream of exon 2 (containing the ATG start codon). A floxed neomycin resistance cassette was also inserted in intron 3. The resistance cassette was removed prior to blastocyst injection, presumably by transient cre excision. This left exons 2 and 3 flanked by loxP sites. Miced with this floxed allele were then crossed to mice carrying a Zp3-cre transgene to produce the deleted allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Flip<d>,
  • Flip<d>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele