First Author | Kumar S | Year | 1992 |
Journal | Biochem Biophys Res Commun | Volume | 185 |
Issue | 3 | Pages | 1155-61 |
PubMed ID | 1378265 | Mgi Jnum | J:1344 |
Mgi Id | MGI:49871 | Doi | 10.1016/0006-291x(92)91747-e |
Citation | Kumar S, et al. (1992) Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun 185(3):1155-61 |
abstractText | Using a subtraction cloning approach, we have isolated a set of cDNA clones from mouse neural precursor cells whose respective mRNA levels are down-regulated during the development of mouse brain. Single stranded DNA prepared from neuronal precursor cell cDNA library in lambda Zap vector was subtracted with poly (A)+ RNA prepared from postnatal and adult mouse brain to obtain several clones which show developmental down-regulation of expression. Their patterns of expression indicate that these genes may play important roles during the embryonic development and differentiation of central nervous system. |