Primary Identifier | MGI:6283658 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Siglecg |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3834 |
molecularNote | ENU-induced A to G transition at base pair 43,409,422 (v38) on chromosome 7, or base pair 1,230 in the GenBank genomic region NC_000073. The mutation corresponds to residue 743 in the mRNA sequence NM_172900 within exon 4 of 12 total exons. The mutation results in a serine to glycine substitution at position 200 (S200G) in the Siglec-G protein. |