Primary Identifier | MGI:2178217 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 100986 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including potassium channel regulator activity; protein kinase A regulatory subunit binding activity; and transmembrane transporter binding activity. Acts upstream of or within Sertoli cell development and spermatogenesis. Located in several cellular components, including 9+2 motile cilium; microtubule organizing center; and subapical part of cell. Is expressed in central nervous system; pancreas epithelium; and retina. Human ortholog(s) of this gene implicated in long QT syndrome 11. Orthologous to human AKAP9 (A-kinase anchoring protein 9). PHENOTYPE: Mice homozygous for a chemically induced allele exhibit male infertily with abnormal spermatogenesis and Sertoli maturation. [provided by MGI curators] |