| Primary Identifier | MGI:2663628 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gpx4 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | All of the exons of the endogenous locus, encompassing the entire coding regions of the mitochondrial, non-mitochondrial, and sperm nuclei isoforms, were replaced with a neomycin selection cassette inserted by homologous recombination. Reduced levels of transcript and protein were observed in various tissues obtained from heterozygous mutant mice. |
