|  Help  |  About  |  Contact Us

Allele : Pan3<em1(IMPC)Tcp> PAN3 poly(A) specific ribonuclease subunit; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6367973 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Pan3
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1408 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CATGGAGGATGTACCAAACA targeting the 5' side and AGCAGAATACTCCTAGTAGA targeting the 3' side of a critical region. This resulted in a 635-bp del Chr5:147450462-47451096; 4-bp del Chr5: 147451260-147451263. The 635-bp deletion represents the Cas9-mediated deletion while the 4-bp deletion is likely a strain-specific polymorphism (GRCm38).
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele