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Protein Coding Gene : Tpt1 tumor protein, translationally-controlled 1
Primary Identifier  MGI:104890 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  22070
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA-binding transcription factor binding activity. Involved in negative regulation of ectoderm development and stem cell population maintenance. Located in nucleoplasm. Is expressed in cerebral cortex ventricular layer; cortical plate; sciatic nerve; and testis. Orthologous to several human genes including TPT1 (tumor protein, translationally-controlled 1).
PHENOTYPE: Mice homozygous for a knock-out allele die prior to embryo turning due to defects in embryogenesis. [provided by MGI curators]
  • synonyms:
  • Tpt1,
  • tumor protein, translationally-controlled 1,
  • translationally regulated transcript (21 kDa),
  • Trt,
  • TCTP,
  • MGD-MRK-29043,
  • fortilin
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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