| Primary Identifier | MGI:94902 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13392 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and nucleic acid binding activity. Involved in negative regulation of photoreceptor cell differentiation; positive regulation of amacrine cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including negative regulation of oligodendrocyte differentiation; nervous system development; and skeletal system development. Located in nucleus. Is expressed in several structures, including branchial arch; embryo ectoderm; genitourinary system; sensory organ; and tooth. Orthologous to human DLX2 (distal-less homeobox 2). PHENOTYPE: Homozygous null mutants show morphogenetic abnormalities in first and second branchial arch-derived proximal skeletal and soft tissue structures; in double mutants with a Dlx1 null allele, maxillary molar teeth are missing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
