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Allele : Arid1b<em1Hzhu> AT-rich interaction domain 1B; endonuclease-mediated mutation 1, Hao Zhu

Primary Identifier  MGI:6116819 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Arid1b
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was deleted using CRISPR/Cas9 mutagenesis. qPCR analysis revealed that mRNA transcripts were reduced in the liver, whole brain, pituitary gland, dentate gyrus, and hypothalamus of heterozygous mutant mice. Western blot analysis confirmed the reduction of protein levels in heterozygous P0 limbs and P45 whole brain extracts, and the absence of protein in homozygous P0 mutant pups.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Arid1b<delta>,
  • Arid1b<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele