| Primary Identifier | MGI:1316726 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 14161 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Acts upstream of or within blood coagulation. Located in cell cortex. Is active in synapse. Is expressed in several structures, including heart; liver; lung; nephron; and telencephalon. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; familial visceral amyloidosis; and thrombophilia. Orthologous to human FGA (fibrinogen alpha chain). PHENOTYPE: Mice homozygous for disruptions of this gene have blood that is unable to clot. On some genetic backgrounds this can lead to fatal hemorrhaging. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
