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Protein Coding Gene : Spag16 sperm associated antigen 16

Primary Identifier  MGI:1913972 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  66722
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein kinase binding activity. Involved in cilium assembly. Acts upstream of or within cerebrospinal fluid circulation; mucociliary clearance; and sperm axoneme assembly. Located in axonemal central apparatus and sperm flagellum. Orthologous to human SPAG16 (sperm associated antigen 16).
PHENOTYPE: Chimeric males carrying one copy of the mutated allele have impaired spermatogenesis, a significant loss of germ cells at the round spermatid stage, and disorganized sperm axoneme structure. No offspring carrying the mutated allele are produced from matings using male chimeras. [provided by MGI curators]
  • synonyms:
  • 4930585K05Rik,
  • expressed sequence AV261009,
  • sperm associated antigen 16,
  • Pf20,
  • Wdr29,
  • AV261009,
  • Spag16,
  • MGI:1923198,
  • RIKEN cDNA 4930524F24 gene,
  • MGI:2138527,
  • RIKEN cDNA 4930585K05 gene,
  • MGI:1922324,
  • RIKEN cDNA 4921511D23 gene,
  • 4930524F24Rik,
  • 4921511D23Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For