| Primary Identifier | MGI:96963 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 17287 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable metallodipeptidase activity and metalloendopeptidase activity. Predicted to be involved in epidermal growth factor receptor ligand maturation. Predicted to act upstream of or within proteolysis. Located in membrane. Is expressed in several structures, including gut and metanephros. Orthologous to human MEP1A (meprin A subunit alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased litter size, reduced LPS-induced renal injury and bladder inflammation, and increased susceptibility to sodium dextran sulfate-induced colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
