| First Author | Koiwai O | Year | 1995 |
| Journal | Biochem Genet | Volume | 33 |
| Issue | 3-4 | Pages | 111-22 |
| PubMed ID | 7677729 | Mgi Jnum | J:25115 |
| Mgi Id | MGI:72828 | Doi | 10.1007/BF00557949 |
| Citation | Koiwai O, et al. (1995) Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations. Biochem Genet 33(3-4):111-22 |
| abstractText | The mouse gene for phenol UDP-glucuronosyltransferase (UDPGT; Ugtla1) was mapped at 42 cM on chromosome 1, a position identical to that of the gene for bilirubin UDPGT (Ugtla1), from linkage analysis of a three-point cross test with Idh-1, En-1, and Ugtla1 as marker genes. The cDNAs for mouse phenol and bilirubin UDPGTs, isolated after amplification by PCR, shared an identical 3'-half region. Our results strongly suggest that mouse bilirubin and phenol UDPGTs are expressed from a single gene and involve alternative splicing events. We also detected duplication of the gene for phenol UDPGT in all mouse strains examined with the exception of MOL-MIT and SUB-SHH. |
