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Allele : Il4/Il13<tm3Anjm> interleukin 4; targeted mutation 3, Andrew NJ McKenzie
Primary Identifier  MGI:3038244 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination results in the deletion of a 15 kb region from exon 3 of the Il13 locus to intron 3 of the Il4 locus. RT-PCR and ELISAs failed to detect any Il4 or Il13 mRNA in activated lymphocytes or protein in stimulated CD4+ T-cells.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • Il-4/13<->,
  • Il-4<->Il-13<->,
  • Il-4/13<->,
  • Il-4<->Il-13<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

76 Publication categories

Trail: Allele




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