| Primary Identifier | MGI:1930003 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 58218 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane signaling receptor activity. Involved in positive regulation of innate immune response. Acts upstream of or within neutrophil chemotaxis; neutrophil extravasation; and neutrophil-mediated killing of gram-negative bacterium. Predicted to be located in plasma membrane. Predicted to be active in cell surface. Is expressed in renal vasculature. PHENOTYPE: Mice homozygous for a knock-out allele of Trem1 and Trem3 exhibit increased susceptibility to P. aeruginosa infection with reduced neutrophil transepithelial migration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
