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Allele : Htra2<tm1.2Hohj> HtrA serine peptidase 2; targeted mutation 1.2, Josephine Hoh
Primary Identifier  MGI:5752863 Allele Type  Targeted
Attribute String  Null/knockout Gene  Htra2
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 through 4. Western blotting confirmed loss of protein in brain, spleen, and thymus tissues from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • HTRA2 KO,
  • HTRA2 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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