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Allele : Tg(CAG-SNCA*)1.1Ccs transgene insertion 1.1, Christine C Stichel

Primary Identifier  MGI:3764813 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(CAG-SNCA*)1.1Ccs
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
description  Four lines were created (1.10, 1.1, 1.5 and 1,9) with similar expression patterns and line 1.1 choosen as the representative line.
molecularNote  This transgene contains a double mutant human SNCA with amino acid substitutions of proline for alanine at position 30 (A30P) and threonine for alanine at position 53 (A53T) under the control of a CMV enchanced, chicken beta-actin promoter. Expression is detected in the brain, kidney, lung, liver and heart.
  • mutations:
  • Insertion
  • synonyms:
  • BAsyn,
  • Tg(ACTB-SNCA*)1.1Ccs,
  • Tg(CAG-SNCA*)1.1Ccs,
  • BAsyn,
  • chbetaactin,
  • Tg(ACTB-SNCA*)1.1Ccs,
  • Tg(CAG-SNCA*)1.1Ccs,
  • chbetaactin
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele