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Publication : Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody specific for the S antigen of hepatitis B virus.

First Author  Ryu CJ Year  1994
Journal  Gene Volume  144
Issue  2 Pages  313-4
PubMed ID  8039721 Mgi Jnum  J:19746
Mgi Id  MGI:67879 Doi  10.1016/0378-1119(94)90398-0
Citation  Ryu CJ, et al. (1994) Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody specific for the S antigen of hepatitis B virus. Gene 144(2):313-4
abstractText  The nucleotide (nt) sequences encoding the variable regions of the heavy and light chains of a murine monoclonal antibody (mAb) have been determined. The mAb recognizes a disulfide-bond-dependent conformational epitope on the hepatitis B virus surface antigen. The sequence analyses revealed that the variable regions of the heavy and light chains are members of mouse heavy-chain subgroup II(A) and kappa light-chain subgroup III, respectively.
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