Primary Identifier | MGI:2178082 | Allele Type | Targeted |
Gene | Grin1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This allele is a derivative of Grin1tm1Phs. Point mutations were introduced that altered codon 598 in exon 15 from one encoding asparagine to one encoding glutamine. A loxP-flanked neomycin selection cassette in intron 18 was removed by transient Cre recombinase expression in ES cells prior to the production of chimeric mice. |