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Publication : Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas.

First Author  Selander L Year  2002
Journal  Mech Dev Volume  113
Issue  2 Pages  189-92
PubMed ID  11960711 Mgi Jnum  J:76547
Mgi Id  MGI:2179659 Doi  10.1016/s0925-4773(02)00023-0
Citation  Selander L, et al. (2002) Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech Dev 113(2):189-92
abstractText  Stem cell research and the prospect of stem cell based therapies depend critically on the identification of specific markers that can be used for the identification and selection of stem and progenitor cells. Nestin is expressed in neuronal progenitor cells and has also been suggested to mark multipotent pancreatic stem cells. We show here that, throughout pancreatic development, markers of pancreatic progenitor cells and differentiated pancreatic cells are expressed in E-cadherin-positive epithelial cells that do not express nestin. The data presented demonstrate that nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas.
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