Primary Identifier | MGI:5550456 | Allele Type | Targeted |
Gene | Card14 | Transmission | Germline |
Strain of Origin | C57BL/6N-A<tm1Brd> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Glycine codon 117 was changed to a serine codon (p.G117S) through a G-to-A point mutation, and an FRT flanked neomycin selection cassette inserted into intron 5. The mutation mimics a psoriasis-associated mutation in human. |