| Primary Identifier | MGI:1913096 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 57748 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables transcription coactivator activity. Involved in actin nucleation; actin polymerization-dependent cell motility; and positive regulation of apoptotic process. Acts upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in skeletal muscle. Orthologous to human JMY (junction mediating and regulatory protein, p53 cofactor). PHENOTYPE: Mice homozygous for a conditional allele activated in Sertoli cells exhibit reduced male fertility, oligozoospermia, asthenozoospermia, enlarged sperm head, and impaired Sertoli cell function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
