| Primary Identifier | MGI:6305310 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Irf8 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3514 |
| molecularNote | ENU-induced T to C transition at base pair 120,753,707 (v38) on chromosome 8, or base pair 17,350 in the GenBank genomic region NC_000074 encoding Irf8. The mutation corresponds to residue 1,009 in the mRNA sequence NM_008320 within exon 7 of 9 total exons. The mutation results in substitution of valine for an alanine at position 319 (V319A) in the IRF8 protein. |
