|  Help  |  About  |  Contact Us

Allele : Gk<tm1Wjc> glycerol kinase; targeted mutation 1, William J Craigen

Primary Identifier  MGI:2429928 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gk
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encompassing all of exons 13 and 14 as well as a portion of exon 15 was replaced with a neomycin selection cassette. mRNA was undetected by Northern blot analysis of liver tissue obtained from homozygous mutant mice. A biochemical assay showed glycerol kinase activity to be reduced by over 95% in liver, kidney, and brown fat.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele