| Primary Identifier | MGI:6285772 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Ptprc |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3821 |
| molecularNote | ENU-induced A to T transversion at base pair 138,083,567 (v38) on chromosome 1, or base pair 92,190 in the GenBank genomic region NC_000067 encoding Ptprc. The mutation corresponds to residue 1,960 in the mRNA sequence NM_011210 within exon 19 of 30 total exons. The mutation results in an asparagine to isoleucine substitution at position 747 (N747I) in variant 1 of the CD45 protein, an N608I substitution in variant 2, and an N584I substitution in variant 3. |
