Primary Identifier | MGI:107633 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 17035 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Enables metalloendopeptidase inhibitor activity. Acts upstream of or within detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in cartilage; central nervous system; peripheral nervous system; and tibia. Orthologous to human LXN (latexin). PHENOTYPE: Mice homozygous for a targeted null mutation display reduced sensitivity to acute thermal pain, which can be reversed by exogenous carboxypeptidase inhibitor. [provided by MGI curators] |