First Author | McCarthy MM | Year | 1975 |
Journal | J Immunol | Volume | 115 |
Issue | 5 | Pages | 1327-9 |
PubMed ID | 1176777 | Mgi Jnum | J:5567 |
Mgi Id | MGI:54044 | Doi | 10.4049/jimmunol.115.5.1327 |
Citation | McCarthy MM, et al. (1975) The humoral response of mouse spleen cells to two types of sheep erythrocytes. III. A new VH region marker. J Immunol 115(5):1327-9 |
abstractText | It was previously shown that there is multigene control of the response of mouse spleen cells to two types of sheep erythrocytes (H and L). Discriminator strains of mice make a much higher response to extra antigens found only on H SRBC than to the shared antigens found on both types of erythrocyte. Non-discriminator strains respond only to the shared antigens, making a response as great as the discriminator response to the extra antigens. In this study we have shown that the response to the extra antigen(s) on H SRBC is under the genetic control of a gene(s) located in the VH region near or to the left of the A5a, alpha 1, 3-dextran and NP makers. |