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Allele : Tg(Csf1r*-GAL4/VP16,UAS-ECFP)1Hume transgene insertion 1, David A Hume
Primary Identifier  MGI:5587942 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Csf1r*-GAL4/VP16,UAS-ECFP)1Hume
Strain of Origin  (C57BL/6J x CBA)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Two transgenes inserted at a single locus. One transgenic construct is designed with a colony stimulating factor 1 receptor (Csf1r) promoter, lacking the 158 bp (-454 to -298 relative to ATG) trophoblast transcription start sites and a TATA-box. This mutated Csf1r drives expression of a "Gal4 driver" (containing a yeast GAL4 transcriptional activator fused to herpes simplex virus protein (VP16)). A "Gal4-responder" plasmid is designed to contain an enhanced cyan fluorescent protein (ECFP) uder the control of a yeast upstream activating sequence (UAS) Gal4-dependent promoter. The founder line with approximately 5% ECFP+ leukocytes was selected for characterization.
  • mutations:
  • Insertion
  • synonyms:
  • MacBlue,
  • Csf1r-Gal4VP16/UAS-ECFP,
  • MacBlue,
  • Csf1r-Gal4VP16/UAS-ECFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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