Primary Identifier | MGI:1931143 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Cd19 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | true | Is Wild Type | false |
molecularNote | In-frame insertion of a cre recombinase gene into the first coding exon followed by an fFRT site flanked neomycin resistance gene cassette. A frameshift mutation was also introduced into exon 5. This allele expresses cre recombinase specifically in B lineage cells throughout development. |