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Protein Coding Gene : Dynlt2a1 dynein light chain Tctex-type 2A1
Primary Identifier  MGI:98642 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  21647
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable dynein intermediate chain binding activity. Acts upstream of or within microtubule-based movement. Located in cytosol; membrane; and sperm flagellum. Part of cytoplasmic dynein complex. Is expressed in forelimb bud. Orthologous to human DYNLT2 (dynein light chain Tctex-type 2).
PHENOTYPE: Mice homozygous for a targeted allele exhibit some male infertility, oligozoospermia, asthenozoospermia, and abnormal sperm morphology. [provided by MGI curators]
  • synonyms:
  • t-complex testis-expressed 4,
  • MGI:98648,
  • t-complex testis-expressed 2,
  • dynein light chain Tctex-type 2,
  • MGI:6458567,
  • D17Leh117c,
  • MGD-MRK-14953,
  • Tctex2,
  • MGD-MRK-14955,
  • MGI:6459776,
  • dynein light chain Tctex-type 2A1,
  • MGD-MRK-14967,
  • MGD-MRK-14945,
  • Tctex4,
  • MGI:6456863,
  • Dynlt2a1,
  • Tctex-2,
  • Dynlt2,
  • LC2,
  • Tcte-3,
  • Tctex-4,
  • MGD-MRK-14969,
  • Tcte3,
  • t-complex-associated testis expressed 3,
  • MGD-MRK-4499,
  • MGD-MRK-14948
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