Primary Identifier | MGI:3808720 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Ascl3 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | true | Is Wild Type | false |
molecularNote | Exon 2, which contains the entire coding region of the gene, was replaced by targeting vector consisting of an EGFP/Cre-recombinase fusion gene followed by a floxed neomycin selection cassette. This targeting event generates a null allele. The EGFP/Cre-recombinase fusion product was detected in duct cells of the submandibular, sublingual and parotid glands. |