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Publication : Mammalian SP/KLF transcription factors: bring in the family.

First Author  Suske G Year  2005
Journal  Genomics Volume  85
Issue  5 Pages  551-6
PubMed ID  15820306 Mgi Jnum  J:97532
Mgi Id  MGI:3575608 Doi  10.1016/j.ygeno.2005.01.005
Citation  Suske G, et al. (2005) Mammalian SP/KLF transcription factors: Bring in the family. Genomics 85(5):551-6
abstractText  The advent of the genome projects has provided new avenues to explore the question of how DNA sequence information is used appropriately by mammalian cells. Regulation of transcription is not the only, but is certainly a very important, mechanism involved in this process. We can now identify all the genes encoding transcription factors belonging to a certain class and study their biological functions in unprecedented detail through the use of an array of biomolecular tools. It is important to use rigorous and uniform definitions for the classification of transcription factors, because this helps us to comprehend the functions of transcription factor families in biological networks. Here, we propose an unambiguous nomenclature for the members of the Specificity Protein/Kruppel-like Factor (SP/KLF) transcription factor family.
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