| Primary Identifier | MGI:3712860 | Allele Type | Spontaneous |
| Gene | Sgk3 | Inheritance Mode | Recessive |
| Strain of Origin | (129S6/SvEvTac x C57BL/6J)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mutation is a 2.4-kb genomic deletion encompassing part of intron 17, exon 18, and sequences encoding the 3'-untranslated region (3'-UTR) of the mRNA. This deletion would result in termination of protein translation at valine 440 (Val440Ter) and thus loss of the 55 C-terminal amino acids, which include the entire C-terminal protein kinase C-like domain. |
