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Protein Coding Gene : Pgrmc2 progesterone receptor membrane component 2

Primary Identifier  MGI:1918054 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  70804
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; neural retina; pharyngo-tympanic tube; and submandibular gland primordium. Orthologous to human PGRMC2 (progesterone receptor membrane component 2).
PHENOTYPE: Mice homozygous for a conditional allele activated in the uterus exhibit early female reproductive senescence, decreased uterine NK cell number, increased endometrial gland number and uterine cysts. [provided by MGI curators]
  • synonyms:
  • progesterone receptor membrane component 2,
  • Pgrmc2,
  • DG6,
  • RIKEN cDNA 5730409G06 gene,
  • MGI:1917743,
  • 4631434O19Rik,
  • RIKEN cDNA 4631434O19 gene,
  • 5730409G06Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For